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Human Growth Hormone?
New molecular technologies in biology have made it possible to insert the gene for human growth hormone (HGH) into the DNA of bacteria. The bacteria that take up the HGH gene are able to transcribe and translate this gene into small quantities of HGH, which can be harvested and given to people with HGH-related growth disorders. What fundamental similarities must bacteria and humans share in order to make this technology possible?
Public Comments
- Similar DNA. that is no secret.
- do your own homework.
- The fundamental similarity between the two, is the presence of DNA in their nucleus, and the triplet of bases or "codons" that limit such hormones aminoacids..because, a segment of the human chain (gene) will be inserted in to a "break" of the bacterial DNA by means of especific endonucleases... Once the human gene is inserted by endo nucleases, and the desired portion of DNA that produce the 92 aminoacid sequence of the polypeptide that forms the Human Growth Hormone, will produce the sought sequence of mRNA produced by he active portio of human DNA, that by then, has become a, "Exon"....(active open portion of uncoiled DNA) The answer is DNA. and the most used bacteria for the purpose, is E. coli, non patogenic strains..(its easier to insert a portion of foregn DNA because the bacterial DNA is linear) its easier to split by endonucleases, and accept the new gene...(even when its an human gene)...
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